The Microbiome-Metabolism Connection
Metabolic disorders like obesity and T2D are increasingly prevalent and pose significant clinical challenges. Emerging research indicates that the gut microbiome—the complex community of microbes residing in the human intestinal tract—plays a pivotal role in host metabolism. Importantly, these microbes produce metabolites influenced by dietary factors, which in turn affect glucose and lipid levels in the blood. In the MicroDiet project, we integrated extensive clinical, dietary, and microbiota data, acquired through our ZONMW JPI HDHL project, to create a comprehensive dataset that powers the MicroDiet prediction tool.